Metabolaid syndrome métabolique

Zeropollution: an active ingredient to pollution-induced skin damage

The pollution : a major health concern

According to the WHO, 9in10 of the world’s population breath a high polluted air. Pollution is a major health concern nowadays.
The sources of pollution vary from natural sources such as volcanic and human activities to automobiles and factories. The pollutants of major concern regarding public health are mainly particulate matter, carbon monoxide, ozone, nitrogen dioxide and sulphur dioxide. (Environnemental Protection Agency).
Pollution causes the death of several millions of people each year. The fine particles of polluted air enter the body, the lungs and the cardiovascular system, causing diseases such as strokes, serious respiratory infections.
Pollution, fortunately, does not always have such a fatal outcome but affects every individual on a daily basis.

Consequences of pollution on the skin

The skin is the first barrier of the organism against external agression. It is already affected by UV leading to dryness and ageing.Repeated pollution exposure is also one of the major threats for skin health. Pollution contributes to extrinsic skin ageing (pigment spots on the face, nasolabial folds, and wrinkles) and is an aggravating factor in several inflammatory or allergic skin conditions, such as atopic dermatitis, eczema, psoriasis or acne. The combination of UV radiation and pollution have a very bad uptake on skin. That is why protecting our skin is very important.

Zeropollution : an oral solution to protect and repair the skin

Zeropollution is an oral solution to pollution induced skin damages. It is a blend of 4 plants extracts that act synergistically and complementarily to protect and repair the visible skin damage caused by pollution and amplified by exposure to UV.

Human cell model studies show the role of Zeropollution.
The cells are treated with Zeropollution extract and allow a significant decrease of the oxidant stress (measurement of ROS level Reactive Oxygen Species) when exposed to urban dust and UV radiation.
Another test is done with skin explants exposed to Pollutants (Heavy metals, hydrocarbons and Diesel particles) 1 h after being in contact with Zeropollution. The results show that Zeropollution could inhibit one of the major biological pathways of pollutant stress response.
The pollutant- induced Aryl hydrocarbon receptor (AhR) activation increases the expression of genes responsible for changes in barrier function, melanogenesis, inflammation, in addition to inducing oxidative stress.

A clinical study on the effects of zeropollution is currently running
For more information, contact us !

Sources :
• Organisation mondiale de la Santé
• Environnemental Protection Agency
• Monteleoder

8 November 2018