Lipocal Highly bioavailable source of calcium of non-animal origin

Lipocal is a microencaspulated mineral and water-dispersible micronised source of calcium. It offers improved bioavailability.

Lipocal is from non-animal origin and suitable for vegetarians.

Lipocal is available in France and Benelux countries.


Lipocal contains 36% calcium in the form of tricalcium phosphate and 18% phosphorus.

The main properties of Lipocal are:

  • A highly bioavailable source of calcium
  • Improved dispersibility
  • High calcium concentration
  • More bioavailable than other sources of calcium
  • Non-animal source of calcium
  • Suitable for vegetarians
  • Easy to incorporate

Nutrition and Health Benefits

Lipocal offers benefits to bones & teeth health in both adults and infants thanks to its highly bioavailable source of calcium.

The bioavailability efficacy of Lipocal has been tested in 25 guinea pigs.

Trials were conducted on four groups of five male guinea pigs, with administration of 3.43 mg calcium per kg of body weight and three different sources of calcium: tricalcium phosphate, Lipocal and dairy calcium (study performed at the University of Barcelona). The absorption profile of calcium during 50 minutes was determined and the overall uptake over time was calculated (figure 1).

Profil d'absorption du calcium

Figure 1 : Comparison of blood calcium concentration over time
[Source : Lipofoods].


Calcium administration induces higher blood calcium concentration. The maximum is obtained 20 minutes after administration. Results show a greater increase in calcium blood concentration in animals with Lipocal administration than in the others (figure 1).

The corresponding area under the curve (AUC) values were then calculated (figure 2). Plasma calcium concentration for each source of calcium was estimated measuring the amount of calcium absorbed during the experimental period.

Absorption totale calcium

Figure 2 : Total absorption of Lipocal and other calcium sources
[Source : Lipofoods]. AUC (0-40min)


The three groups : TCP,  milk calcium (dairy calcium) and Lipocal were statistically different (p<0.05). The absorption difference was calculated and results were : Lipocal is 41% more available than TCP and Lipocal is 15% more bioavailable than dairy calcium.

In conclusion, Lipocal, a micronised and microencaspulated source of calcium, induces a faster increase in calcium blood concentration and is a highly bioavailable source of calcium.


Sources :

  • Lipofoods document, presentation of Lipocal
  • Lipofoods (2004) Microencapsulated tricalcium phosphate with improved dispersibility and enhanced bioavailability
  • Trial done by Dr. Joana Planas, Dep. de Fisiologia, Facultadde Farmacia, Universidad de Barcelona

Regulatory Information

Lipocal can be used in:

  • Foods as permitted under Regulation (EC) No. 1925/2006 on the addition of vitamins and minerals and certain other substances to foods (Annex 1);
  • Food supplementsas permitted under Directive 2002/46/EC (Annex 1) on the approximation of the laws of the Member States relating to food supplements;
  • Foods for particular nutritional uses as permitted under Commission Regulation (EC) No. 953/2009 on substances that may be added for specific nutritional purposes in foods for particular nutritional uses;
  • Infant formulae as permitted under Commission Directive 2006/141/EC on infant formulae and follow-on formulae and amending Directive 1999/21/EC;
  • Cereals and baby foods as permitted under Commission Directive 2006/125/EC on processed cereal-based foods and baby foods for infants and young children

According to the Annex XIII of Regulation (EU) No. 1169/2011 on the provision of food information to consumers, the significant amount of calcium is :

  • 15% of the nutrient reference values (NRV) specified in point 1 supplied by 100g or 100ml in the case of products other than beverages;
  • 5% of the NRV specified in point 1 supplied by 100ml in the case of beverages;
  • 15% of the NRV specified in point 1 per portion if the package contains only a single portion.

Technological Properties and Formulation

Lipocal is available in white powder form.

The Nutrient Reference Value (NRV) for calcium is 800mg per day in Europe.

Lipocal can be easily incorporated in a wide range of food applications such as milk and dairy products, infant formula, soy products, bakery products, beverages, food supplements, etc.

It can also be considered suitable to fortify food products designed for those suffering from allergies or intolerances or those  who do not consume dairy products.

Nutrition and Health Claims

Nutrition Claims

According to Regulation (EC) No. 1924/2006 of the European Parliament and of the Council of 20 December 2006 on nutrition and health claims, foods and beverages with added calcium may be labelled:

  • Source of Calcium” if they contain at least 15% of the recommended daily allowance (RDA) per 100g, 100ml or per portion;
  • High in Calcium” if they contain at least 30% of the RDA per 100g, 100ml or per portion.

Health Claims

According to the Commission Regulation (EU) No. 432/2012 (Article 13.1), calcium has the following health claims:

  • Calcium contributes to normal blood clotting
  • Calcium contributes to normal energy-yielding metabolism
  • Calcium contributes to normal muscle function
  • Calcium contributes to normal neurotransmission
  • Calcium contributes to the normal function of digestive enzymes
  • Calcium has a role in the process of cell division and specialisation
  • Calcium is needed for the maintenance of normal bones
  • Calcium is needed for the maintenance of normal teeth

The claim may be used only for food which is at least a source of calcium as referred to in the claim SOURCE OF [NAME OF VITAMIN(S)] AND/OR [NAME OF MINERAL(S)] as listed in the Annex to Regulation (EC) No. 1924/2006.